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Combined In Silico, In Vivo, and In Vitro Studies Shed Insights into the Acute Inflammatory Response in Middle-Aged Mice
We combined in silico, in vivo, and in vitro studies to gain insights into age-dependent changes in acute inflammation in response to bacterial endotoxin (LPS). Time-course cytokine, chemokine, and NO(2) (−/)NO(3) (−) data from “middle-aged” (6–8 months old) C57BL/6 mice were used to re-parameterize...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699569/ https://www.ncbi.nlm.nih.gov/pubmed/23844008 http://dx.doi.org/10.1371/journal.pone.0067419 |