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Two Distinct States of the HAMP Domain from Sensory Rhodopsin Transducer Observed in Unbiased Molecular Dynamics Simulations

HAMP domain is a ubiquitous module of bacterial and archaeal two-component signaling systems. Considerable progress has been made recently in studies of its structure and conformational changes. However, the mechanism of signal transduction through the HAMP domain is not clear. It remains a question...

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Detalles Bibliográficos
Autores principales: Gushchin, Ivan, Gordeliy, Valentin, Grudinin, Sergei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699570/
https://www.ncbi.nlm.nih.gov/pubmed/23843970
http://dx.doi.org/10.1371/journal.pone.0066917