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Amyloid-β Protofibrils: Size, Morphology and Synaptotoxicity of an Engineered Mimic
Structural and biochemical studies of the aggregation of the amyloid-β peptide (Aβ) are important to understand the mechanisms of Alzheimer's disease, but research is complicated by aggregate inhomogeneity and instability. We previously engineered a hairpin form of Aβ called Aβcc, which forms s...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699592/ https://www.ncbi.nlm.nih.gov/pubmed/23843949 http://dx.doi.org/10.1371/journal.pone.0066101 |