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Iduronic Acid in Chondroitin/Dermatan Sulfate Affects Directional Migration of Aortic Smooth Muscle Cells

Aortic smooth muscle cells produce chondroitin/dermatan sulfate (CS/DS) proteoglycans that regulate extracellular matrix organization and cell behavior in normal and pathological conditions. A unique feature of CS/DS proteoglycans is the presence of iduronic acid (IdoA), catalyzed by two DS epimeras...

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Detalles Bibliográficos
Autores principales: Bartolini, Barbara, Thelin, Martin A., Svensson, Lena, Ghiselli, Giancarlo, van Kuppevelt, Toin H., Malmström, Anders, Maccarana, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699603/
https://www.ncbi.nlm.nih.gov/pubmed/23843960
http://dx.doi.org/10.1371/journal.pone.0066704