The Proton Pump Inhibitor Lansoprazole Improves the Skeletal Phenotype in Dystrophin Deficient mdx Mice

BACKGROUND: In Duchenne muscular dystrophy (DMD), loss of the membrane stabilizing protein dystrophin results in myofiber damage. Microinjury to dystrophic myofibers also causes secondary imbalances in sarcolemmic ion permeability and resting membrane potential, which modifies excitation-contraction...

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Detalles Bibliográficos
Autores principales: Sali, Arpana, Many, Gina M., Gordish-Dressman, Heather, van der Meulen, Jack H., Phadke, Aditi, Spurney, Christopher F., Cnaan, Avital, Hoffman, Eric P., Nagaraju, Kanneboyina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699610/
https://www.ncbi.nlm.nih.gov/pubmed/23843959
http://dx.doi.org/10.1371/journal.pone.0066617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699610/
https://www.ncbi.nlm.nih.gov/pubmed/23843959
http://dx.doi.org/10.1371/journal.pone.0066617

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