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Identification of Residues Involved in Substrate Specificity and Cytotoxicity of Two Closely Related Cutinases from Mycobacterium tuberculosis

The enzymes belonging to the cutinase family are serine enzymes active on a large panel of substrates such as cutin, triacylglycerols, and phospholipids. In the M. tuberculosis H37Rv genome, seven genes coding for cutinase-like proteins have been identified with strong immunogenic properties suggest...

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Detalles Bibliográficos
Autores principales: Dedieu, Luc, Serveau-Avesque, Carole, Canaan, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699616/
https://www.ncbi.nlm.nih.gov/pubmed/23843969
http://dx.doi.org/10.1371/journal.pone.0066913