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Are C-Reactive Protein Associated Genetic Variants Associated with Serum Levels and Retinal Markers of Microvascular Pathology in Asian Populations from Singapore?

INTRODUCTION: C-reactive protein (CRP) levels are associated with cardiovascular disease and systemic inflammation. We assessed whether CRP-associated loci were associated with serum CRP and retinal markers of microvascular disease, in Asian populations. METHODS: Genome-wide association analysis (GW...

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Detalles Bibliográficos
Autores principales: Dorajoo, Rajkumar, Li, Ruoying, Ikram, Mohammad Kamran, Liu, Jianjun, Froguel, Philippe, Lee, Jeannette, Sim, Xueling, Ong, Rick Twee-Hee, Tay, Wan Ting, Peng, Chen, Young, Terri L., Blakemore, Alexandra I. F., Cheng, Ching Yu, Aung, Tin, Mitchell, Paul, Wang, Jie Jin, Klaver, Caroline C., Boerwinkle, Eric, Klein, Ronald, Siscovick, David S., Jensen, Richard A., Gudnason, Vilmundur, Smith, Albert Vernon, Teo, Yik Ying, Wong, Tien Yin, Tai, E-Shyong, Heng, Chew-Kiat, Friedlander, Yechiel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699653/
https://www.ncbi.nlm.nih.gov/pubmed/23844046
http://dx.doi.org/10.1371/journal.pone.0067650