Exocyst Sec5 Regulates Exocytosis of Newcomer Insulin Granules Underlying Biphasic Insulin Secretion

The exocyst complex subunit Sec5 is a downstream effector of RalA-GTPase which promotes RalA-exocyst interactions and exocyst assembly, serving to tether secretory granules to docking sites on the plasma membrane. We recently reported that RalA regulates biphasic insulin secretion in pancreatic isle...

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Detalles Bibliográficos
Autores principales: Xie, Li, Zhu, Dan, Kang, Youhou, Liang, Tao, He, Yu, Gaisano, Herbert Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699660/
https://www.ncbi.nlm.nih.gov/pubmed/23844030
http://dx.doi.org/10.1371/journal.pone.0067561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699660/
https://www.ncbi.nlm.nih.gov/pubmed/23844030
http://dx.doi.org/10.1371/journal.pone.0067561

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