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Exocyst Sec5 Regulates Exocytosis of Newcomer Insulin Granules Underlying Biphasic Insulin Secretion

The exocyst complex subunit Sec5 is a downstream effector of RalA-GTPase which promotes RalA-exocyst interactions and exocyst assembly, serving to tether secretory granules to docking sites on the plasma membrane. We recently reported that RalA regulates biphasic insulin secretion in pancreatic isle...

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Detalles Bibliográficos
Autores principales:	Xie, Li, Zhu, Dan, Kang, Youhou, Liang, Tao, He, Yu, Gaisano, Herbert Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699660/ https://www.ncbi.nlm.nih.gov/pubmed/23844030 http://dx.doi.org/10.1371/journal.pone.0067561

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