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Arginase as a Mediator of Diabetic Retinopathy

We have shown previously that diabetes causes increases in retinal arginase activity that are associated with impairment of endothelial cell (EC)-dependent vasodilation and increased formation of the peroxynitrite biomarker nitrotyrosine. Arginase blockade normalizes vasodilation responses and reduc...

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Detalles Bibliográficos
Autores principales: Patel, Chintan, Rojas, Modesto, Narayanan, S. Priya, Zhang, Wenbo, Xu, Zhimin, Lemtalsi, Tahira, Jittiporn, Kanjana, Caldwell, R. William, Caldwell, Ruth B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699717/
https://www.ncbi.nlm.nih.gov/pubmed/23840196
http://dx.doi.org/10.3389/fimmu.2013.00173