Cargando…

Arginase as a Mediator of Diabetic Retinopathy

We have shown previously that diabetes causes increases in retinal arginase activity that are associated with impairment of endothelial cell (EC)-dependent vasodilation and increased formation of the peroxynitrite biomarker nitrotyrosine. Arginase blockade normalizes vasodilation responses and reduc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Patel, Chintan, Rojas, Modesto, Narayanan, S. Priya, Zhang, Wenbo, Xu, Zhimin, Lemtalsi, Tahira, Jittiporn, Kanjana, Caldwell, R. William, Caldwell, Ruth B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699717/ https://www.ncbi.nlm.nih.gov/pubmed/23840196 http://dx.doi.org/10.3389/fimmu.2013.00173

Ejemplares similares

Retinal Neuroprotection From Optic Nerve Trauma by Deletion of Arginase 2
por: Xu, Zhimin, et al.
Publicado: (2018)

Targeting proliferative retinopathy: Arginase 1 limits vitreoretinal neovascularization and promotes angiogenic repair
por: Fouda, Abdelrahman Y., et al.
Publicado: (2022)

Mechanisms of Diabetes-Induced Endothelial Cell Senescence: Role of Arginase 1
por: Shosha, Esraa, et al.
Publicado: (2018)

NOX2-Induced Activation of Arginase and Diabetes-Induced Retinal Endothelial Cell Senescence
por: Rojas, Modesto, et al.
Publicado: (2017)

Role of Arginase 2 in Murine Retinopathy Associated with Western Diet-Induced Obesity
por: Atawia, Reem T., et al.
Publicado: (2020)

Is the Arginase Pathway a Novel Therapeutic Avenue for Diabetic Retinopathy?
por: Shosha, Esraa, et al.
Publicado: (2020)

Arginase 2 promotes neurovascular degeneration during ischemia/reperfusion injury
por: Shosha, Esraa, et al.
Publicado: (2016)

Arginase 1 Mediates Increased Blood Pressure and Contributes to Vascular Endothelial Dysfunction in Deoxycorticosterone Acetate-Salt Hypertension
por: Toque, Haroldo A., et al.
Publicado: (2013)

Calbindin 2-specific deletion of arginase 2 preserves visual function after optic nerve crush
por: Zaidi, Syed A. H., et al.
Publicado: (2023)

Requirement of NOX2 Expression in Both Retina and Bone Marrow for Diabetes-Induced Retinal Vascular Injury
por: Rojas, Modesto, et al.
Publicado: (2013)

Endothelial arginase 2 mediates retinal ischemia/reperfusion injury by inducing mitochondrial dysfunction
por: Shosha, Esraa, et al.
Publicado: (2021)

Arginase 2 deficiency reduces hyperoxia-mediated retinal neurodegeneration through the regulation of polyamine metabolism
por: Narayanan, S P, et al.
Publicado: (2014)

Arginase 1 promotes retinal neurovascular protection from ischemia through suppression of macrophage inflammatory responses
por: Fouda, Abdelrahman Y., et al.
Publicado: (2018)

Investigation of Retinal Metabolic Function in Type 1 Diabetic Akita Mice
por: Shosha, Esraa, et al.
Publicado: (2022)

Arginase 2 Deletion Reduces Neuro-Glial Injury and Improves Retinal Function in a Model of Retinopathy of Prematurity
por: Narayanan, Subhadra P., et al.
Publicado: (2011)

Systemic Administration of Pegylated Arginase-1 Attenuates the Progression of Diabetic Retinopathy
por: Abdelrahman, Ammar A., et al.
Publicado: (2022)

Arginase 2 Deficiency Prevents Oxidative Stress and Limits Hyperoxia-Induced Retinal Vascular Degeneration
por: Suwanpradid, Jutamas, et al.
Publicado: (2014)

Arginase Pathway in Acute Retina and Brain Injury: Therapeutic Opportunities and Unexplored Avenues
por: Fouda, Abdelrahman Y., et al.
Publicado: (2020)

Role of acyl-coenzyme A: cholesterol transferase 1 (ACAT1) in retinal neovascularization
por: Zaidi, Syed A. H., et al.
Publicado: (2023)

Arginase in the Vascular Endothelium: Friend or Foe?
por: Lucas, Rudolf, et al.
Publicado: (2014)

Deletion of arginase 2 attenuates neuroinflammation in an experimental model of optic neuritis
por: Candadai, Amritha A., et al.
Publicado: (2021)

Angiotensin II-Induced Arterial Thickening, Fibrosis and Stiffening Involves Elevated Arginase Function
por: Bhatta, Anil, et al.
Publicado: (2015)

Correction: Angiotensin II-Induced Arterial Thickening, Fibrosis and Stiffening Involves Elevated Arginase Function
por: Bhatta, Anil, et al.
Publicado: (2015)

Akita Spontaneously Type 1 Diabetic Mice Exhibit Elevated Vascular Arginase and Impaired Vascular Endothelial and Nitrergic Function
por: Toque, Haroldo A., et al.
Publicado: (2013)

Methylglyoxal-Modified Albumin Effects on Endothelial Arginase Enzyme and Vascular Function
por: Alzayadneh, Ebaa M., et al.
Publicado: (2023)

Arginase 1: An Unexpected Mediator of Pulmonary Capillary Barrier Dysfunction in Models of Acute Lung Injury
por: Lucas, Rudolf, et al.
Publicado: (2013)

Utility of LysM-cre and Cdh5-cre Driver Mice in Retinal and Brain Research: An Imaging Study Using tdTomato Reporter Mouse
por: Fouda, Abdelrahman Y., et al.
Publicado: (2020)

Novel Therapeutics for Diabetic Retinopathy and Diabetic Macular Edema: A Pathophysiologic Perspective
por: Bunch, Katharine L., et al.
Publicado: (2022)

Targeting Polyamine Oxidase to Prevent Excitotoxicity-Induced Retinal Neurodegeneration
por: Pichavaram, Prahalathan, et al.
Publicado: (2019)

Role of Arginase in Vessel Wall Remodeling
por: Durante, William
Publicado: (2013)

Arginase Promotes Skeletal Muscle Arteriolar Endothelial Dysfunction in Diabetic Rats
por: Johnson, Fruzsina K., et al.
Publicado: (2013)

Endoplasmic reticulum stress-regulated CXCR3 pathway mediates inflammation and neuronal injury in acute glaucoma
por: Ha, Y, et al.
Publicado: (2015)

Triciribine attenuates pathological neovascularization and vascular permeability in a mouse model of proliferative retinopathy
por: Shan, Shengshuai, et al.
Publicado: (2023)

Selective Up-Regulation of Arginase-1 in Coronary Arteries of Diabetic Patients
por: Bagi, Zsolt, et al.
Publicado: (2013)

Evolutionary Roots of Arginase Expression and Regulation
por: Dzik, Jolanta Maria
Publicado: (2014)

Arginase-1 Is Responsible for IL-13-Mediated Susceptibility to Trypanosoma cruzi Infection
por: Abad Dar, Mahin, et al.
Publicado: (2018)

Development of Novel Arginase Inhibitors for Therapy of Endothelial Dysfunction
por: Steppan, Jochen, et al.
Publicado: (2013)

Myeloid Cell-Derived Arginase in Cancer Immune Response
por: Grzywa, Tomasz M., et al.
Publicado: (2020)

Acrolein: A Potential Mediator of Oxidative Damage in Diabetic Retinopathy
por: Alfarhan, Moaddey, et al.
Publicado: (2020)

The arginase 1/ornithine decarboxylase pathway suppresses HDAC3 to ameliorate the myeloid cell inflammatory response: implications for retinal ischemic injury
por: Shosha, Esraa, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_elvs1d4re1jj89hs54bar72fof