Prognostic impact and the relevance of PTEN copy number alterations in patients with advanced colorectal cancer (CRC) receiving bevacizumab*

Loss of phosphatase and tensin homologue (PTEN) expression may be prognostic in colorectal cancer (CRC) and may have a correlation with vascular endothelial growth factor (VEGF) expression via hypoxia-inducible factor 1 (HIF-1) alpha, and the PI3K/mTOR pathways. We therefore have explored the progno...

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Detalles Bibliográficos
Autores principales: Price, Timothy J, Hardingham, Jennifer E, Lee, Chee K, Townsend, Amanda R, Wrin, Joseph W, Wilson, Kate, Weickhardt, Andrew, Simes, Robert J, Murone, Carmel, Tebbutt, Niall C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699839/
https://www.ncbi.nlm.nih.gov/pubmed/23930204
http://dx.doi.org/10.1002/cam4.75

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699839/
https://www.ncbi.nlm.nih.gov/pubmed/23930204
http://dx.doi.org/10.1002/cam4.75

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