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7-Aza-des-A-steroids with Antimicrobial and Cytotoxic Activity

This paper describes a convenient approach to the 7-aza-des-A-steroid (6,6a,7,8,9,9a-hexahydro-5H-cyclopenta[h]quinoline) scaffold starting from Grundmann’s ketone using two different pyridine annulation protocols. The biological evaluation of the pyridine and pyridinium products revealed that these...

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Detalles Bibliográficos
Autores principales: Krojer, Melanie, Keller, Marco, Bracher, Franz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700069/
https://www.ncbi.nlm.nih.gov/pubmed/23833707
http://dx.doi.org/10.3797/scipharm.1303-03