Cargando…

7-Aza-des-A-steroids with Antimicrobial and Cytotoxic Activity

This paper describes a convenient approach to the 7-aza-des-A-steroid (6,6a,7,8,9,9a-hexahydro-5H-cyclopenta[h]quinoline) scaffold starting from Grundmann’s ketone using two different pyridine annulation protocols. The biological evaluation of the pyridine and pyridinium products revealed that these...

Descripción completa

Detalles Bibliográficos
Autores principales:	Krojer, Melanie, Keller, Marco, Bracher, Franz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Österreichische Apotheker-Verlagsgesellschaft 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700069/ https://www.ncbi.nlm.nih.gov/pubmed/23833707 http://dx.doi.org/10.3797/scipharm.1303-03

Ejemplares similares

Aza Analogs of the TRPML1 Inhibitor Estradiol Methyl Ether (EDME)
por: Rühl, Philipp, et al.
Publicado: (2023)

New Substituted Isocoumarins and Dihydroisocoumarins and their Cytotoxic Activities
por: Hampl, Veronika, et al.
Publicado: (2011)

Endophytic Fusarium solani: A rich source of cytotoxic and antimicrobial napthaquinone and aza-anthraquinone derivatives
por: Khan, Nasima, et al.
Publicado: (2018)

The Gramine Route to Pyrido[4,3-b]indol-3-ones – Identification of a New Cytotoxic Lead
por: Wollein, Uwe, et al.
Publicado: (2011)

The 7-azanorbornane nucleus of epibatidine: 7-azabicyclo[2.2.1]heptan-7-ium chloride
por: Britvin, Sergey N., et al.
Publicado: (2017)

Synthesis by Ring-Closing Metathesis and Cytotoxic Evaluation of Novel Thienylmacrolactones
por: Krauss, Jürgen, et al.
Publicado: (2012)

The Synthesis of Novel aza-Steroids and α, β-Unsaturated-Cyanoketone from Diosgenin
por: Mesa, Dayana, et al.
Publicado: (2023)

7-Aminoheptylazanium iodide
por: Reiss, Guido J.
Publicado: (2011)

Antimicrobial Activity of Some Steroidal Hydrazones
por: Merlani, Maia, et al.
Publicado: (2023)

The enzymatic biosynthesis of acylated steroidal glycosides and their cytotoxic activity
por: Liu, Ming, et al.
Publicado: (2018)

The ethoxycarbonyl group as both activating and protective group in N-acyl-Pictet–Spengler reactions using methoxystyrenes. A short approach to racemic 1-benzyltetrahydroisoquinoline alkaloids
por: Keller, Marco, et al.
Publicado: (2021)

The antileukaemic activity of 5-Aza-2 deoxycytidine (Aza-dC) in patients with relapsed and resistant leukaemia.
por: Richel, D. J., et al.
Publicado: (1991)

Investigation of 8-Aza-7-Deaza Purine Nucleoside Derivatives
por: Ren, Hang, et al.
Publicado: (2019)

Cytotoxicity and Antimicrobial Activity of Oral Rinses In Vitro
por: Müller, Heinz-Dieter, et al.
Publicado: (2017)

Synthesis and Anticancer Evaluation of Novel 7-Aza-Coumarine-3-Carboxamides
por: Trifonov, Alexey V., et al.
Publicado: (2023)

Steroidal Glycosides from Convallaria majalis Whole Plants and Their Cytotoxic Activity
por: Matsuo, Yukiko, et al.
Publicado: (2017)

Antiproliferative, Cytotoxic, and Apoptotic Activity of Steroidal Oximes in Cervicouterine Cell Lines
por: Sánchez-Sánchez, Luis, et al.
Publicado: (2016)

(-)-Shikimic Acid as a Chiral Building Block for the Synthesis of New Cytotoxic 6-Aza-Analogues of Angucyclinones
por: Quiñones, Natalia, et al.
Publicado: (2018)

Functionalization of 4-bromobenzo[c][2,7]naphthyridine via regioselective direct ring metalation. A novel approach to analogues of pyridoacridine alkaloids
por: Melzer, Benedikt C, et al.
Publicado: (2019)

Cytotoxic furanosesquiterpenoids and steroids from Ircinia mutans sponges
por: Heidary Jamebozorgi, Fatemeh, et al.
Publicado: (2021)

1,10a-Dihydro-1-aza-10a-boraphenanthrene and 6a,7-Dihydro-7-aza-6a-boratetraphene: Two New Fluorescent BN-PAHs
por: Valencia, Isabel, et al.
Publicado: (2021)

(Aza)Pentacenes Clipped into a Ring: Stabilization of Large (Aza)Acenes
por: Ahrens, Lukas, et al.
Publicado: (2021)

Transformation of Thia[7]helicene to Aza[7]helicenes and [7]Helicene-like Compounds via Aromatic Metamorphosis
por: Uematsu, Keisuke, et al.
Publicado: (2022)

Aminomethylation/hydrogenolysis as an alternative to direct methylation of metalated isoquinolines – a novel total synthesis of the alkaloid 7-hydroxy-6-methoxy-1-methylisoquinoline
por: Melzer, Benedikt C, et al.
Publicado: (2018)

Cytotoxic and antimicrobial activity of selected Cameroonian edible plants
por: Dzoyem, Jean Paul, et al.
Publicado: (2013)

Synthesis and antiviral activity of a series of 1′-substituted 4-aza-7,9-dideazaadenosine C-nucleosides
por: Cho, Aesop, et al.
Publicado: (2012)

Synthesis of Trichodermin Derivatives and Their Antimicrobial and Cytotoxic Activities
por: Barúa, Javier E., et al.
Publicado: (2019)

Polyoxygenated Steroids from the Octocoral Leptogorgia punicea and in Vitro Evaluation of Their Cytotoxic Activity
por: Moritz, Maria Izabel G., et al.
Publicado: (2014)

Synthesis and Cytotoxic Evaluation of Steroidal Copper (Cu (II)) Complexes
por: Huang, Yanmin, et al.
Publicado: (2017)

Antioxidant, antimicrobial and cytotoxic activities of gold nanoparticles capped with quercetin
por: Milanezi, Felipe Guzansky, et al.
Publicado: (2019)

Cytotoxic Steroidal Saponins from the Flowers of Allium leucanthum
por: Mskhiladze, Lasha, et al.
Publicado: (2008)

Antimicrobial, Antiparasitic, Anti-Inflammatory, and Cytotoxic Activities of Lopezia racemosa
por: Cruz Paredes, Carla, et al.
Publicado: (2013)

Antimicrobial, Anti-Inflammatory, Antiparasitic, and Cytotoxic Activities of Laennecia confusa
por: Martínez Ruiz, María G., et al.
Publicado: (2012)

Phytochemicals from Kaempferia angustifolia Rosc. and Their Cytotoxic and Antimicrobial Activities
por: Tang, Sook Wah, et al.
Publicado: (2014)

The Influence of Carrier Oils on the Antimicrobial Activity and Cytotoxicity of Essential Oils
por: Orchard, Ané, et al.
Publicado: (2019)

Cytotoxic, antioxidant, and antimicrobial activities of Celery (Apium graveolens L.)
por: Aboody, Mohammed Saleh Al
Publicado: (2021)

Antimicrobial and Cytotoxic Activity of Endophytic Fungi from Lagopsis supina
por: Zhang, Dekui, et al.
Publicado: (2023)

Three cheers for nitrogen: aza-DKPs, the aza analogues of 2,5-diketopiperazines
por: Maujean, Timothé, et al.
Publicado: (2020)

6,7-Diphenyl-5-thia-7-azaspiro[2.6]nonan-8-one
por: Yennawar, Hemant P., et al.
Publicado: (2013)

New Flexible Analogues of 8-Aza-7-deazapurine Nucleosides as Potential Antibacterial Agents
por: Khandazhinskaya, Anastasia, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_q9kkmtikputo9nl98tqqm655cc