Combinatorial Effects of Thymoquinone on the Anticancer Activity and Hepatotoxicity of the Prodrug CB 1954

BACKGROUND: One of the major causes of clinical trial termination is the liver toxicity induced by chemotherapeutic agents. Treatment with anticancer drugs like CB 1954 (5-(Aziridin-1-yl)-2,4-dinitrobenzamide) is associated with significant hepatotoxicity. Thymoquinone (TQ), extracted from Nigella s...

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Detalles Bibliográficos
Autores principales: Talib, Wamidh H., AbuKhader, Majed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700079/
https://www.ncbi.nlm.nih.gov/pubmed/23833717
http://dx.doi.org/10.3797/scipharm.1211-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700079/
https://www.ncbi.nlm.nih.gov/pubmed/23833717
http://dx.doi.org/10.3797/scipharm.1211-15

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