Simultaneous Neutralization and Innate Immune Detection of a Replicating Virus by TRIM21

Tripartite motif-containing 21 (TRIM21) is a cytosolic immunoglobulin receptor that mediates antibody-dependent intracellular neutralization (ADIN). Here we show that TRIM21 potently inhibits the spreading infection of a replicating cytopathic virus and activates innate immunity. We used a quantitat...

Descripción completa

Detalles Bibliográficos
Autores principales: Watkinson, R. E., Tam, J. C. H., Vaysburd, M. J., James, L. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2013
Materias:
Virus-Cell Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700317/
https://www.ncbi.nlm.nih.gov/pubmed/23596308
http://dx.doi.org/10.1128/JVI.00647-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700317/
https://www.ncbi.nlm.nih.gov/pubmed/23596308
http://dx.doi.org/10.1128/JVI.00647-13

Ejemplares similares