Uromodulin Upregulates TRPV5 by Impairing Caveolin-Mediated Endocytosis

Uromodulin (UMOD) is synthesized in the thick ascending limb and secreted into urine as the most abundant protein. Association studies in humans suggest protective effects of UMOD against calcium-containing kidney stones. Mice carrying mutations of Umod found in human uromodulin-associated kidney di...

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Detalles Bibliográficos
Autores principales: Wolf, Matthias T.F., Wu, Xue-Ru, Huang, Chou-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700562/
https://www.ncbi.nlm.nih.gov/pubmed/23466996
http://dx.doi.org/10.1038/ki.2013.63

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700562/
https://www.ncbi.nlm.nih.gov/pubmed/23466996
http://dx.doi.org/10.1038/ki.2013.63

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