Cargando…

Uromodulin Upregulates TRPV5 by Impairing Caveolin-Mediated Endocytosis

Uromodulin (UMOD) is synthesized in the thick ascending limb and secreted into urine as the most abundant protein. Association studies in humans suggest protective effects of UMOD against calcium-containing kidney stones. Mice carrying mutations of Umod found in human uromodulin-associated kidney di...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wolf, Matthias T.F., Wu, Xue-Ru, Huang, Chou-Long
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700562/ https://www.ncbi.nlm.nih.gov/pubmed/23466996 http://dx.doi.org/10.1038/ki.2013.63

Ejemplares similares

Engineering caveolin-mediated endocytosis in Saccharomyces cerevisiae
por: Zhang, Qian, et al.
Publicado: (2022)

Endocytosis of Connexin 36 is Mediated by Interaction with Caveolin-1
por: Kotova, Anna, et al.
Publicado: (2020)

Serum uromodulin is associated with impaired glucose metabolism
por: Leiherer, Andreas, et al.
Publicado: (2017)

Cigarette smoke increases susceptibility to infection in lung epithelial cells by upregulating caveolin-dependent endocytosis
por: Duffney, Parker F., et al.
Publicado: (2020)

Uromodulin and Estrogen
por: Intapad, Suttira
Publicado: (2023)

Leishmania donovani Internalizes into Host Cells via Caveolin-mediated Endocytosis
por: Kumar, G. Aditya, et al.
Publicado: (2019)

Impact of Caveolin-Mediated Endocytosis on the Trafficking of HIV within the Colonic Barrier
por: Anwar, Alex, et al.
Publicado: (2022)

Nucleosomes enter cells by clathrin- and caveolin-dependent endocytosis
por: Wang, Huawei, et al.
Publicado: (2021)

Intracellular Trafficking Pathways of Edwardsiella tarda: From Clathrin- and Caveolin-Mediated Endocytosis to Endosome and Lysosome
por: Sui, Zhi-hai, et al.
Publicado: (2017)

Endocytic Crosstalk: Cavins, Caveolins, and Caveolae Regulate Clathrin-Independent Endocytosis
por: Chaudhary, Natasha, et al.
Publicado: (2014)

Uromodulin deficiency alters tubular injury and interstitial inflammation but not fibrosis in experimental obstructive nephropathy
por: Maydan, Olena, et al.
Publicado: (2018)

Hints to the diagnosis of uromodulin kidney disease
por: Onoe, Tamehito, et al.
Publicado: (2016)

Role of Uromodulin in Salt-Sensitive Hypertension
por: Mary, Sheon, et al.
Publicado: (2022)

Salt stress in the renal tubules is linked to TAL-specific expression of uromodulin and an upregulation of heat shock genes
por: Graham, Lesley A., et al.
Publicado: (2018)

Lef1 regulates caveolin expression and caveolin dependent endocytosis, a process necessary for Wnt5a/Ror2 signaling during Xenopus gastrulation
por: Puzik, Katharina, et al.
Publicado: (2019)

Avian Reovirus σB Interacts with Caveolin-1 in Lipid Rafts during Dynamin-Dependent Caveolae-Mediated Endocytosis
por: Wang, Yuyang, et al.
Publicado: (2022)

Caveolin-1 and CDC42 mediated endocytosis of silica-coated iron oxide nanoparticles in HeLa cells
por: Bohmer, Nils, et al.
Publicado: (2015)

Serum uromodulin in dogs with chronic kidney disease
por: Seo, Dansong, et al.
Publicado: (2022)

Uromodulin Retention in Thick Ascending Limb of Henle's Loop Affects SCD1 in Neighboring Proximal Tubule: Renal Transcriptome Studies in Mouse Models of Uromodulin-Associated Kidney Disease
por: Horsch, Marion, et al.
Publicado: (2014)

IGF1R Signaling in Ewing Sarcoma Is Shaped by Clathrin-/Caveolin-Dependent Endocytosis
por: Martins, Ana Sofia, et al.
Publicado: (2011)

Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells
por: Bourseau-Guilmain, E., et al.
Publicado: (2016)

Demonstration of the Clathrin- and Caveolin-Mediated Endocytosis at the Maternal–Fetal Barrier in Mouse Placenta after Intravenous Administration of Gold Nanoparticles
por: RATTANAPINYOPITUK, Kasem, et al.
Publicado: (2013)

JNTX-101, a novel albumin-encapsulated gemcitabine prodrug, is efficacious and operates via caveolin-1-mediated endocytosis
por: Cui, Tiantian, et al.
Publicado: (2023)

Capsaicin upregulates HDAC2 via TRPV1 and impairs neuronal maturation in mice
por: Wang, Sung Eun, et al.
Publicado: (2018)

Serum uromodulin—a marker of kidney function and renal parenchymal integrity
por: Scherberich, Jürgen E, et al.
Publicado: (2018)

Diagnosis and Long-term Management of Uromodulin Kidney Disease
por: Wheeler, Emily, et al.
Publicado: (2019)

The Urinary Excretion of Uromodulin is Regulated by the Potassium Channel ROMK
por: Schiano, Guglielmo, et al.
Publicado: (2019)

Role of uromodulin and complement activation in the progression of kidney disease
por: Shen, Fei, et al.
Publicado: (2021)

Low serum uromodulin levels and their association with lupus flares
por: David, Bonilla-Lara, et al.
Publicado: (2022)

Uromodulin and Vesico-Ureteral Reflux: A Genetic Study
por: Maringhini, Silvio, et al.
Publicado: (2023)

Hepsin-mediated Processing of Uromodulin is Crucial for Salt-sensitivity and Thick Ascending Limb Homeostasis
por: Olinger, Eric, et al.
Publicado: (2019)

Cell-specific NFIA upregulation promotes epileptogenesis by TRPV4-mediated astrocyte reactivity
por: Kong, Shuo, et al.
Publicado: (2023)

The serine protease hepsin mediates urinary secretion and polymerisation of Zona Pellucida domain protein uromodulin
por: Brunati, Martina, et al.
Publicado: (2015)

Caveolin-1 regulation of dynamin-dependent, raft-mediated endocytosis of cholera toxin–B sub-unit occurs independently of caveolae
por: Lajoie, Patrick, et al.
Publicado: (2009)

Clathrin- and caveolin-1–independent endocytosis: entry of simian virus 40 into cells devoid of caveolae
por: Damm, Eva-Maria, et al.
Publicado: (2005)

Caveolin-1–dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo
por: Marchiando, Amanda M., et al.
Publicado: (2010)

Exosome Uptake Depends on ERK1/2-Heat Shock Protein 27 Signaling and Lipid Raft-mediated Endocytosis Negatively Regulated by Caveolin-1
por: Svensson, Katrin J., et al.
Publicado: (2013)

Uromodulin-related autosomal-dominant tubulointerstitial kidney disease—pathogenetic insights based on a case
por: Reindl, Johanna, et al.
Publicado: (2018)

Serum uromodulin and progression of kidney disease in patients with chronic kidney disease
por: Lv, Li, et al.
Publicado: (2018)

Urinary uromodulin, kidney function and cardiovascular disease in elderly adults
por: Garimella, Pranav S., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_50o402pa2b41pue351sr7864q6