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Hidden hysteresis – population dynamics can obscure gene network dynamics

BACKGROUND: Positive feedback is a common motif in gene regulatory networks. It can be used in synthetic networks as an amplifier to increase the level of gene expression, as well as a nonlinear module to create bistable gene networks that display hysteresis in response to a given stimulus. Using a...

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Detalles Bibliográficos
Autores principales: Poisson, Phillip, Bhalerao, Kaustubh D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700772/
https://www.ncbi.nlm.nih.gov/pubmed/23800122
http://dx.doi.org/10.1186/1754-1611-7-16