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Hidden hysteresis – population dynamics can obscure gene network dynamics
BACKGROUND: Positive feedback is a common motif in gene regulatory networks. It can be used in synthetic networks as an amplifier to increase the level of gene expression, as well as a nonlinear module to create bistable gene networks that display hysteresis in response to a given stimulus. Using a...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700772/ https://www.ncbi.nlm.nih.gov/pubmed/23800122 http://dx.doi.org/10.1186/1754-1611-7-16 |