Impaired proteasomal degradation enhances autophagy via hypoxia signaling in Drosophila

BACKGROUND: Two pathways are responsible for the majority of regulated protein catabolism in eukaryotic cells: the ubiquitin-proteasome system (UPS) and lysosomal self-degradation through autophagy. Both processes are necessary for cellular homeostasis by ensuring continuous turnover and quality con...

Descripción completa

Detalles Bibliográficos
Autores principales: Lőw, Péter, Varga, Ágnes, Pircs, Karolina, Nagy, Péter, Szatmári, Zsuzsanna, Sass, Miklós, Juhász, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700814/
https://www.ncbi.nlm.nih.gov/pubmed/23800266
http://dx.doi.org/10.1186/1471-2121-14-29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700814/
https://www.ncbi.nlm.nih.gov/pubmed/23800266
http://dx.doi.org/10.1186/1471-2121-14-29

Ejemplares similares