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Comparative DNA methylation among females with neurodevelopmental disorders and seizures identifies TAC1 as a MeCP2 target gene

BACKGROUND: Several proteins involved in epigenetic regulation cause syndromic neurodevelopmental disorders when human genes are mutated. More general involvement of epigenetic mechanisms in neurodevelopmental phenotypes is unclear. METHODS: In an attempt to determine whether DNA methylation differe...

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Detalles Bibliográficos
Autores principales: Aldinger, Kimberly A, Plummer, Jasmine T, Levitt, Pat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700820/
https://www.ncbi.nlm.nih.gov/pubmed/23759142
http://dx.doi.org/10.1186/1866-1955-5-15