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Contribution of nucleosome binding preferences and co-occurring DNA sequences to transcription factor binding

BACKGROUND: Chromatin plays a critical role in regulating transcription factors (TFs) binding to their canonical transcription factor binding sites (TFBS). Recent studies in vertebrates show that many TFs preferentially bind to genomic regions that are well bound by nucleosomes in vitro. Co-occurrin...

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Detalles Bibliográficos
Autores principales: He, Ximiao, Chatterjee, Raghunath, John, Sam, Bravo, Hector, Sathyanarayana, B K, Biddie, Simon C, FitzGerald, Peter C, Stamatoyannopoulos, John A, Hager, Gordon L, Vinson, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700821/
https://www.ncbi.nlm.nih.gov/pubmed/23805837
http://dx.doi.org/10.1186/1471-2164-14-428