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The role of uPAR in epithelial-mesenchymal transition in small airway epithelium of patients with chronic obstructive pulmonary disease

BACKGROUND: Epithelial-mesenchymal transition (EMT) plays a crucial role in small airway fibrosis of patients with chronic obstructive pulmonary disease (COPD). Increasing evidence suggests that the urokinase plasminogen activator receptor (uPAR) is involved in the pathogenesis of COPD. Increased uP...

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Detalles Bibliográficos
Autores principales: Wang, Qin, Wang, Yunshan, Zhang, Yi, Zhang, Yuke, Xiao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700841/
https://www.ncbi.nlm.nih.gov/pubmed/23806081
http://dx.doi.org/10.1186/1465-9921-14-67