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Spontaneous Atopic Dermatitis-Like Symptoms in a/a ma ft/ma ft/J Flaky Tail Mice Appear Early after Birth

Loss-of-function mutations in human profilaggrin gene have been identified as the cause of ichthyosis vulgaris (IV), and as a major predisposition factor for atopic dermatitis (AD). Similarly, flaky tail (a/a ma ft/ma ft/J) mice were described as a model for IV, and shown to be predisposed to eczema...

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Detalles Bibliográficos
Autores principales: Kypriotou, Magdalini, Boéchat, Cloé, Huber, Marcel, Hohl, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700905/
https://www.ncbi.nlm.nih.gov/pubmed/23844115
http://dx.doi.org/10.1371/journal.pone.0067869