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Proteomic Analysis Reveals that Proteasome Subunit Beta 6 Is Involved in Hypoxia-Induced Pulmonary Vascular Remodeling in Rats

BACKGROUND: Chronic hypoxia (CH) is known to be one of the major causes of pulmonary hypertension (PH), which is characterized by sustained elevation of pulmonary vascular resistance resulting from vascular remodeling. In this study, we investigated whether the ubiquitin proteasome system (UPS) was...

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Detalles Bibliográficos
Autores principales: Wang, Jian, Xu, Lei, Yun, Xin, Yang, Kai, Liao, Dongjiang, Tian, Lichun, Jiang, Haiyang, Lu, Wenju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700908/
https://www.ncbi.nlm.nih.gov/pubmed/23844134
http://dx.doi.org/10.1371/journal.pone.0067942