Cargando…

TLR-2/TLR-4 TREM-1 Signaling Pathway Is Dispensable in Inflammatory Myeloid Cells during Sterile Kidney Injury

Inflammatory macrophages are abundant in kidney disease, stimulating repair, or driving chronic inflammation and fibrosis. Damage associated molecules (DAMPs), released from injured cells engage pattern recognition receptors (PRRs) on macrophages, contributing to activation. Understanding mechanisms...

Descripción completa

Detalles Bibliográficos
Autores principales: Campanholle, Gabriela, Mittelsteadt, Kristen, Nakagawa, Shunsaku, Kobayashi, Akio, Lin, Shuei-Liong, Gharib, Sina A., Heinecke, Jay W., Hamerman, Jessica A., Altemeier, William A., Duffield, Jeremy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700949/
https://www.ncbi.nlm.nih.gov/pubmed/23844229
http://dx.doi.org/10.1371/journal.pone.0068640