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Combined Patterns of IGHV Repertoire and Cytogenetic/Molecular Alterations in Monoclonal B Lymphocytosis versus Chronic Lymphocytic Leukemia

BACKGROUND: Chronic lymphocytic leukemia (CLL)-like monoclonal B lymphocytosis (MBL) with (MBL(hi)) or without (MBL(lo)) absolute B-lymphocytosis precedes most CLL cases,the specific determinants for malignant progression remaining unknown. METHODOLOGY/PRINCIPAL FINDINGS: For this purpose, simultane...

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Detalles Bibliográficos
Autores principales: Henriques, Ana, Rodríguez-Caballero, Arancha, Nieto, Wendy G., Langerak, Anton W., Criado, Ignacio, Lécrevisse, Quentin, González, Marcos, Pais, Maria L., Paiva, Artur, Almeida, Julia, Orfao, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701012/
https://www.ncbi.nlm.nih.gov/pubmed/23844084
http://dx.doi.org/10.1371/journal.pone.0067751