Axon Guidance of Sympathetic Neurons to Cardiomyocytes by Glial Cell Line-Derived Neurotrophic Factor (GDNF)

Molecular signaling of cardiac autonomic innervation is an unresolved issue. Here, we show that glial cell line-derived neurotrophic factor (GDNF) promotes cardiac sympathetic innervation in vitro and in vivo. In vitro, ventricular myocytes (VMs) and sympathetic neurons (SNs) isolated from neonatal...

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Detalles Bibliográficos
Autores principales: Miwa, Keiko, Lee, Jong-Kook, Takagishi, Yoshiko, Opthof, Tobias, Fu, Xianming, Hirabayashi, Masumi, Watabe, Kazuhiko, Jimbo, Yasuhiko, Kodama, Itsuo, Komuro, Issei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701054/
https://www.ncbi.nlm.nih.gov/pubmed/23843937
http://dx.doi.org/10.1371/journal.pone.0065202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701054/
https://www.ncbi.nlm.nih.gov/pubmed/23843937
http://dx.doi.org/10.1371/journal.pone.0065202

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