Paclitaxel disrupts polarized entry of membrane-permeable C6 ceramide into ovarian cancer cells resulting in synchronous induction of cell death

Exogenous cell-permeable C6 ceramide has been demonstrated to act synergistically with chemotherapeutic drugs, including paclitaxel, cisplatin, doxorubicin and the histone deacetylase inhibitor, trichostatin A, to induce cell death in a variety of cancer cells. We previously demonstrated that C6 cer...

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Detalles Bibliográficos
Autores principales: BEST, CHARLES, CALIANESE, DAVID, SZULAK, KEVIN, CAMMARATA, GARRET, BRUM, GABRIELLA, CARBONE, THOMAS, STILL, ERIC, HIGGINS, KATELYN, JI, FANG, DI, WEN, WANEBO, HAROLD, WAN, YINSHENG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701061/
https://www.ncbi.nlm.nih.gov/pubmed/23833655
http://dx.doi.org/10.3892/ol.2013.1305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701061/
https://www.ncbi.nlm.nih.gov/pubmed/23833655
http://dx.doi.org/10.3892/ol.2013.1305

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