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Paclitaxel disrupts polarized entry of membrane-permeable C6 ceramide into ovarian cancer cells resulting in synchronous induction of cell death
Exogenous cell-permeable C6 ceramide has been demonstrated to act synergistically with chemotherapeutic drugs, including paclitaxel, cisplatin, doxorubicin and the histone deacetylase inhibitor, trichostatin A, to induce cell death in a variety of cancer cells. We previously demonstrated that C6 cer...
Autores principales: | BEST, CHARLES, CALIANESE, DAVID, SZULAK, KEVIN, CAMMARATA, GARRET, BRUM, GABRIELLA, CARBONE, THOMAS, STILL, ERIC, HIGGINS, KATELYN, JI, FANG, DI, WEN, WANEBO, HAROLD, WAN, YINSHENG |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701061/ https://www.ncbi.nlm.nih.gov/pubmed/23833655 http://dx.doi.org/10.3892/ol.2013.1305 |
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