Cargando…

Comparison of Systemic and Mucosal Immunization with Helper-Dependent Adenoviruses for Vaccination against Mucosal Challenge with SHIV

Most HIV-1 infections are thought to occur at mucosal surfaces during sexual contact. It has been hypothesized that vaccines delivered at mucosal surfaces may mediate better protection against HIV-1 than vaccines that are delivered systemically. To test this, rhesus macaques were vaccinated by intra...

Descripción completa

Detalles Bibliográficos
Autores principales: Weaver, Eric A., Nehete, Pramod N., Nehete, Bharti P., Yang, Guojun, Buchl, Stephanie J., Hanley, Patrick W., Palmer, Donna, Montefiori, David C., Ferrari, Guido, Ng, Philip, Sastry, K. Jagannadha, Barry, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701068/
https://www.ncbi.nlm.nih.gov/pubmed/23844034
http://dx.doi.org/10.1371/journal.pone.0067574