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pK(a) determination of oxysophocarpine by reversed - phase high performance liquid chromatography
BACKGROUND: In this study, a RP - HPLC method was applied for determination of pK(a) value by using the dependence of the capacity factor (k) on the pH of the mobile phase for oxysophocarpine (OSP). FINDINGS: The effect of the mobile phase composition on the ionization constant was studied by measur...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701144/ https://www.ncbi.nlm.nih.gov/pubmed/23853749 http://dx.doi.org/10.1186/2193-1801-2-270 |