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pK(a) determination of oxysophocarpine by reversed - phase high performance liquid chromatography

BACKGROUND: In this study, a RP - HPLC method was applied for determination of pK(a) value by using the dependence of the capacity factor (k) on the pH of the mobile phase for oxysophocarpine (OSP). FINDINGS: The effect of the mobile phase composition on the ionization constant was studied by measur...

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Detalles Bibliográficos
Autores principales: Huo, Huiling, Li, Tingting, Zhang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701144/
https://www.ncbi.nlm.nih.gov/pubmed/23853749
http://dx.doi.org/10.1186/2193-1801-2-270