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Genome editing of human pluripotent stem cells to generate human cellular disease models
Disease modeling with human pluripotent stem cells has come into the public spotlight with the awarding of the Nobel Prize in Physiology or Medicine for 2012 to Drs John Gurdon and Shinya Yamanaka for the discovery that mature cells can be reprogrammed to become pluripotent. This discovery has opene...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Company of Biologists Limited
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701209/ https://www.ncbi.nlm.nih.gov/pubmed/23751357 http://dx.doi.org/10.1242/dmm.012054 |