Norepinephrine transporter variant A457P knock-in mice display key features of human postural orthostatic tachycardia syndrome

Postural orthostatic tachycardia syndrome (POTS) is a common autonomic disorder of largely unknown etiology that presents with sustained tachycardia on standing, syncope and elevated norepinephrine spillover. Some individuals with POTS experience anxiety, depression and cognitive dysfunction. Previo...

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Detalles Bibliográficos
Autores principales: Shirey-Rice, Jana K., Klar, Rebecca, Fentress, Hugh M., Redmon, Sarah N., Sabb, Tiffany R., Krueger, Jessica J., Wallace, Nathan M., Appalsamy, Martin, Finney, Charlene, Lonce, Suzanna, Diedrich, André, Hahn, Maureen K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701219/
https://www.ncbi.nlm.nih.gov/pubmed/23580201
http://dx.doi.org/10.1242/dmm.012203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701219/
https://www.ncbi.nlm.nih.gov/pubmed/23580201
http://dx.doi.org/10.1242/dmm.012203

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