Central and haematopoietic interleukin-1 both contribute to ischaemic brain injury in mice

Interleukin-1 (IL-1) is a key regulator of inflammation and ischaemic brain injury, but the contribution of central and peripheral sources of IL-1 to brain injury is not well understood. Here we show that haematopoietic-derived IL-1 is a key driver of ischaemic brain injury. Wild type (WT) mice tran...

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Detalles Bibliográficos
Autores principales: Denes, Adam, Wilkinson, Fiona, Bigger, Brian, Chu, Michael, Rothwell, Nancy J., Allan, Stuart M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2013
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701223/
https://www.ncbi.nlm.nih.gov/pubmed/23519030
http://dx.doi.org/10.1242/dmm.011601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701223/
https://www.ncbi.nlm.nih.gov/pubmed/23519030
http://dx.doi.org/10.1242/dmm.011601

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