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Introns of plant pri-miRNAs enhance miRNA biogenesis

Plant MIR genes are independent transcription units that encode long primary miRNA precursors, which usually contain introns. For two miRNA genes, MIR163 and MIR161, we show that introns are crucial for the accumulation of proper levels of mature miRNA. Removal of the intron in both cases led to a d...

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Detalles Bibliográficos
Autores principales: Bielewicz, Dawid, Kalak, Malgorzata, Kalyna, Maria, Windels, David, Barta, Andrea, Vazquez, Franck, Szweykowska-Kulinska, Zofia, Jarmolowski, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701235/
https://www.ncbi.nlm.nih.gov/pubmed/23681439
http://dx.doi.org/10.1038/embor.2013.62