Totipotent Embryonic Stem Cells Arise in Ground-State Culture Conditions

Embryonic stem cells (ESCs) are derived from mammalian embryos during the transition from totipotency, when individual blastomeres can make all lineages, to pluripotency, when they are competent to make only embryonic lineages. ESCs maintained with inhibitors of MEK and GSK3 (2i) are thought to repr...

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Detalles Bibliográficos
Autores principales: Morgani, Sophie M., Canham, Maurice A., Nichols, Jennifer, Sharov, Alexei A., Migueles, Rosa Portero, Ko, Minoru S.H., Brickman, Joshua M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701323/
https://www.ncbi.nlm.nih.gov/pubmed/23746443
http://dx.doi.org/10.1016/j.celrep.2013.04.034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701323/
https://www.ncbi.nlm.nih.gov/pubmed/23746443
http://dx.doi.org/10.1016/j.celrep.2013.04.034

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