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Human but Not Mouse Adipogenesis Is Critically Dependent on LMO3

Increased visceral fat is associated with a high risk of diabetes and metabolic syndrome and is in part caused by excessive glucocorticoids (GCs). However, the molecular mechanisms remain undefined. We now identify the GC-dependent gene LIM domain only 3 (LMO3) as being selectively upregulated in a...

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Detalles Bibliográficos
Autores principales: Lindroos, Josefine, Husa, Julia, Mitterer, Gerfried, Haschemi, Arvand, Rauscher, Sabine, Haas, Robert, Gröger, Marion, Loewe, Robert, Kohrgruber, Norbert, Schrögendorfer, Klaus F., Prager, Gerhard, Beck, Harald, Pospisilik, J. Andrew, Zeyda, Maximilian, Stulnig, Thomas M., Patsch, Wolfgang, Wagner, Oswald, Esterbauer, Harald, Bilban, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701325/
https://www.ncbi.nlm.nih.gov/pubmed/23823477
http://dx.doi.org/10.1016/j.cmet.2013.05.020