Uninephrectomy of Diabetic OVE26 Mice Greatly Accelerates Albuminuria, Fibrosis, Inflammatory Cell Infiltration and Changes in Gene Expression

BACKGROUND/AIMS: OVE26 (OVE) mice provide a valuable model of advanced diabetic nephropathy (DN), but they take 8 months to develop moderate interstitial fibrosis and reduced glomerular filtration rate (GFR). The aim of this project was to produce a more rapid and advanced model of DN. METHODS: Unin...

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Detalles Bibliográficos
Autores principales: Zheng, Shirong, Huang, Yun, Yang, Lu, Chen, Teresa, Xu, Jianxiang, Epstein, Paul N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2011
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701440/
https://www.ncbi.nlm.nih.gov/pubmed/21659782
http://dx.doi.org/10.1159/000327586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701440/
https://www.ncbi.nlm.nih.gov/pubmed/21659782
http://dx.doi.org/10.1159/000327586

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