Cargando…

Uninephrectomy of Diabetic OVE26 Mice Greatly Accelerates Albuminuria, Fibrosis, Inflammatory Cell Infiltration and Changes in Gene Expression

BACKGROUND/AIMS: OVE26 (OVE) mice provide a valuable model of advanced diabetic nephropathy (DN), but they take 8 months to develop moderate interstitial fibrosis and reduced glomerular filtration rate (GFR). The aim of this project was to produce a more rapid and advanced model of DN. METHODS: Unin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zheng, Shirong, Huang, Yun, Yang, Lu, Chen, Teresa, Xu, Jianxiang, Epstein, Paul N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	S. Karger AG 2011
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701440/ https://www.ncbi.nlm.nih.gov/pubmed/21659782 http://dx.doi.org/10.1159/000327586

Ejemplares similares

Impaired Albumin Uptake and Processing Promote Albuminuria in OVE26 Diabetic Mice
por: Long, Y. S., et al.
Publicado: (2016)

HIF-1 Mediates Renal Fibrosis in OVE26 Type 1 Diabetic Mice
por: Nayak, Bijaya K., et al.
Publicado: (2016)

Renal Protection by Genetic Deletion of the Atypical Chemokine Receptor ACKR2 in Diabetic OVE Mice
por: Zheng, Shirong, et al.
Publicado: (2016)

Sex Differences in Progression of Diabetic Cardiomyopathy in OVE26 Type 1 Diabetic Mice
por: Tang, Xiaoqiang, et al.
Publicado: (2020)

Therapeutic Effect of MG132 on the Aortic Oxidative Damage and Inflammatory Response in OVE26 Type 1 Diabetic Mice
por: Miao, Xiao, et al.
Publicado: (2013)

Renoprotection From Diabetic Complications in OVE Transgenic Mice by Endothelial Cell Specific Overexpression of Metallothionein: A TEM Stereological Analysis
por: Carlson, Edward C., et al.
Publicado: (2017)

Improvement of Cardiac Functions by Chronic Metformin Treatment Is Associated With Enhanced Cardiac Autophagy in Diabetic OVE26 Mice
por: Xie, Zhonglin, et al.
Publicado: (2011)

Karl-Ove Nielsen, W. Jentschke
por: CERN PhotoLab
Publicado: (1975)

Transcriptome-Based Analysis of Kidney Gene Expression Changes Associated with Diabetes in OVE26 Mice, in the Presence and Absence of Losartan Treatment
por: Komers, Radko, et al.
Publicado: (2014)

Protection against diabetic cardiomyopathy is achieved using a combination of sulforaphane and zinc in type 1 diabetic OVE26 mice
por: Wang, Jiqun, et al.
Publicado: (2019)

Evidence for glucocorticoid-mediated hypertension after uninephrectomy
por: Huesler, Carina, et al.
Publicado: (2013)

Compensatory renal hypertrophy following uninephrectomy is calcineurin-independent
por: Williams, Clintoria R, et al.
Publicado: (2014)

Deletion of the Receptor for Advanced Glycation End Products Reduces Glomerulosclerosis and Preserves Renal Function in the Diabetic OVE26 Mouse
por: Reiniger, Nina, et al.
Publicado: (2010)

Exacerbation of diabetic cardiac hypertrophy in OVE26 mice by angiotensin II is associated with JNK/c-Jun/miR-221-mediated autophagy inhibition
por: Qian, Ling-Bo, et al.
Publicado: (2017)

Angiopoietins Modulate Endothelial Adaptation, Glomerular and Podocyte Hypertrophy after Uninephrectomy
por: Chiang, Wen Chih, et al.
Publicado: (2013)

Rat pancreatectomy combined with isoprenaline or uninephrectomy as models of diabetic cardiomyopathy or nephropathy
por: Thisted, Louise, et al.
Publicado: (2020)

Uninephrectomy-Induced Lipolysis and Low-Grade Inflammation Are Mimicked by Unilateral Renal Denervation
por: Arsenijevic, Denis, et al.
Publicado: (2016)

p47phox contributes to albuminuria and kidney fibrosis in mice
por: Wang, Hongtao, et al.
Publicado: (2015)

Altered Regulation of Renal Sodium Transporters in Salt-Sensitive Hypertensive Rats Induced by Uninephrectomy
por: Jung, Ji Yong, et al.
Publicado: (2009)

Renal injury after uninephrectomy in male and female intrauterine growth-restricted aged rats
por: Newsome, Ashley D., et al.
Publicado: (2019)

Pandora, a PAthway and Network DiscOveRy Approach based on common biological evidence
por: Zhang, Kelvin Xi, et al.
Publicado: (2010)

Impaired ability to modulate glomerular filtration rate in aged female sheep following fetal uninephrectomy
por: Lankadeva, Yugeesh R., et al.
Publicado: (2014)

Tweak induces proliferation in renal tubular epithelium: a role in uninephrectomy induced renal hyperplasia
por: Sanz, Ana B, et al.
Publicado: (2009)

Genetic Abrogation of Adenosine A(3) Receptor Prevents Uninephrectomy and High Salt–Induced Hypertension
por: Yang, Ting, et al.
Publicado: (2016)

Empagliflozin Reduces Renal Hyperfiltration in Response to Uninephrectomy, but Is Not Nephroprotective in UNx/DOCA/Salt Mouse Models
por: Tauber, Philipp, et al.
Publicado: (2021)

Uninephrectomy in rats on a fixed food intake results in adipose tissue lipolysis implicating spleen cytokines
por: Arsenijevic, Denis, et al.
Publicado: (2015)

Experimental uninephrectomy associates with less parasympathetic modulation of heart rate and facilitates sodium-dependent arterial hypertension
por: Pliquett, Rainer U., et al.
Publicado: (2022)

Uninephrectomy in Rats on a Fixed Food Intake Potentiates Both Anorexia and Circulating Cytokine Subsets in Response to LPS
por: Arsenijevic, Denis, et al.
Publicado: (2015)

Blunted Sodium Excretion in Response to a Saline Load in 5 Year Old Female Sheep Following Fetal Uninephrectomy
por: Lankadeva, Yugeesh R., et al.
Publicado: (2012)

Comparison of CT volumetry versus nuclear renography for predicting remaining kidney function after uninephrectomy in living kidney donors
por: Eum, Sang Hun, et al.
Publicado: (2022)

Resveratrol ameliorates the behavioural and molecular changes in rats exposed to uninephrectomy: role of hippocampal SIRT1, BDNF and AChE
por: Basta, Marianne, et al.
Publicado: (2022)

Albuminuria and the Duration of Albuminuria in Cholera
por: Brahmachari, U. N.
Publicado: (1907)

Albuminuria
Publicado: (1890)

Albuminuria
por: Ballenger, Edgar
Publicado: (1908)

Albuminuria
Publicado: (1883)

Albuminuria
por: Reed, W. L.
Publicado: (1893)

Retrospective analysis of the predictive factors of renal function loss after uninephrectomy in patients with chronic kidney disease G3 to G5
por: Dupuis, Dominique, et al.
Publicado: (2015)

Genotypic and phenotypic characterization of the Sdccag8(Tn(sb-Tyr)2161B.CA1C2Ove) mouse model
por: Weihbrecht, Katie, et al.
Publicado: (2018)

Impact of The Daily Mile on children’s physical and mental health, and educational attainment in primary schools: iMprOVE cohort study protocol
por: Ram, Bina, et al.
Publicado: (2021)

Mechanism of Albuminuria Reduction by Chymase Inhibition in Diabetic Mice
por: Terai, Kentaro, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_rfv0aaf4lt10n0ct0mkdii1b67