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DNA methylation analysis reveals distinct methylation signatures in pediatric germ cell tumors

BACKGROUND: Aberrant DNA methylation is a prominent feature of many cancers, and may be especially relevant in germ cell tumors (GCTs) due to the extensive epigenetic reprogramming that occurs in the germ line during normal development. METHODS: We used the Illumina GoldenGate Cancer Methylation Pan...

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Detalles Bibliográficos
Autores principales: Amatruda, James F, Ross, Julie A, Christensen, Brock, Fustino, Nicholas J, Chen, Kenneth S, Hooten, Anthony J, Nelson, Heather, Kuriger, Jacquelyn K, Rakheja, Dinesh, Frazier, A Lindsay, Poynter, Jenny N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701494/
https://www.ncbi.nlm.nih.gov/pubmed/23806198
http://dx.doi.org/10.1186/1471-2407-13-313