LKB1 Inhibits Breast Cancer Partially through Repressing the Hedgehog Signaling Pathway

Constitutive activation of the Hedgehog (Hh) signaling pathway has been implicated in the development of many human malignancies. Hh targets, such as Patched (PTCH), smoothened (SMO), Sonic hedgehog (SHH) and glioma-associated oncogene homologue 1 (GLI1), are markers of Hh signaling activation and e...

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Detalles Bibliográficos
Autores principales: Zhuang, Zhigang, Wang, Kai, Cheng, Xiaolin, Qu, Xueying, Jiang, Beiqi, Li, Zhengdong, Luo, Jianming, Shao, Zhiming, Duan, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701543/
https://www.ncbi.nlm.nih.gov/pubmed/23861764
http://dx.doi.org/10.1371/journal.pone.0067431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701543/
https://www.ncbi.nlm.nih.gov/pubmed/23861764
http://dx.doi.org/10.1371/journal.pone.0067431

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