Wildtype and A30P Mutant Alpha-Synuclein Form Different Fibril Structures

Parkinson’s Disease (PD) is a neurodegenerative movement disorder affecting millions of people worldwide. One of the key players in the development of the disease is the protein α-synuclein (aSN), which aggregates in the brain of PD patients. The aSN mutant A30P has been reported to cause early-onse...

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Detalles Bibliográficos
Autores principales: Nielsen, Søren Bang, Macchi, Francesca, Raccosta, Samuele, Langkilde, Annette Eva, Giehm, Lise, Kyrsting, Anders, Svane, Anna Sigrid Pii, Manno, Mauro, Christiansen, Gunna, Nielsen, Niels Christian, Oddershede, Lene, Vestergaard, Bente, Otzen, Daniel Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701545/
https://www.ncbi.nlm.nih.gov/pubmed/23861789
http://dx.doi.org/10.1371/journal.pone.0067713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701545/
https://www.ncbi.nlm.nih.gov/pubmed/23861789
http://dx.doi.org/10.1371/journal.pone.0067713

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