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Plant Derived Aporphinic Alkaloid S-(+)-Dicentrine Induces Antinociceptive Effect in Both Acute and Chronic Inflammatory Pain Models: Evidence for a Role of TRPA1 Channels

S-(+)-Dicentrine is an aporphinic alkaloid found in several plant species, mainly from Lauraceae family, which showed significant antinociceptive activity in an acute model of visceral pain in mice. In this work, we extended the knowledge on the antinociceptive properties of S-(+)-dicentrine and sho...

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Detalles Bibliográficos
Autores principales: Montrucchio, Deise Prehs, Córdova, Marina Machado, Soares Santos, Adair Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701576/
https://www.ncbi.nlm.nih.gov/pubmed/23861794
http://dx.doi.org/10.1371/journal.pone.0067730