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The Suitability of P. falciparum Merozoite Surface Proteins 1 and 2 as Genetic Markers for In Vivo Drug Trials in Yemen

BACKGROUND: The accuracy of the conclusions from in vivo efficacy anti-malarial drug trials depends on distinguishing between recrudescences and re-infections which is accomplished by genotyping genes coding P. falciparum merozoite surface 1 (MSP1) and MSP2. However, the reliability of the PCR analy...

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Detalles Bibliográficos
Autores principales: Al-abd, Nazeh M., Mahdy, Mohammed A. K., Al-Mekhlafi, Abdulsalam M. Q., Snounou, Georges, Abdul-Majid, Nazia B., Al-Mekhlafi, Hesham M., Fong, Mun Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701615/
https://www.ncbi.nlm.nih.gov/pubmed/23861823
http://dx.doi.org/10.1371/journal.pone.0067853