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Gene Transfection in High Serum Levels: Case Studies with New Cholesterol Based Cationic Gemini Lipids

BACKGROUND: Six new cationic gemini lipids based on cholesterol possessing different positional combinations of hydroxyethyl (-CH(2)CH(2)OH) and oligo-oxyethylene -(CH(2)CH(2)O)(n)- moieties were synthesized. For comparison the corresponding monomeric lipid was also prepared. Each new cationic lipid...

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Detalles Bibliográficos
Autores principales: Misra, Santosh K., Biswas, Joydeep, Kondaiah, Paturu, Bhattacharya, Santanu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701654/
https://www.ncbi.nlm.nih.gov/pubmed/23861884
http://dx.doi.org/10.1371/journal.pone.0068305