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Gene Transfection in High Serum Levels: Case Studies with New Cholesterol Based Cationic Gemini Lipids
BACKGROUND: Six new cationic gemini lipids based on cholesterol possessing different positional combinations of hydroxyethyl (-CH(2)CH(2)OH) and oligo-oxyethylene -(CH(2)CH(2)O)(n)- moieties were synthesized. For comparison the corresponding monomeric lipid was also prepared. Each new cationic lipid...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701654/ https://www.ncbi.nlm.nih.gov/pubmed/23861884 http://dx.doi.org/10.1371/journal.pone.0068305 |