Cargando…
Gene Transfection in High Serum Levels: Case Studies with New Cholesterol Based Cationic Gemini Lipids
BACKGROUND: Six new cationic gemini lipids based on cholesterol possessing different positional combinations of hydroxyethyl (-CH(2)CH(2)OH) and oligo-oxyethylene -(CH(2)CH(2)O)(n)- moieties were synthesized. For comparison the corresponding monomeric lipid was also prepared. Each new cationic lipid...
Autores principales: | Misra, Santosh K., Biswas, Joydeep, Kondaiah, Paturu, Bhattacharya, Santanu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701654/ https://www.ncbi.nlm.nih.gov/pubmed/23861884 http://dx.doi.org/10.1371/journal.pone.0068305 |
Ejemplares similares
-
Gemini Cationic Lipid-Type Nanovectors Suitable for the Transfection of Therapeutic Plasmid DNA Encoding for Pro-Inflammatory Cytokine Interleukin-12
por: Sánchez-Arribas, Natalia, et al.
Publicado: (2021) -
Novel Cholesterol-Based Cationic Lipids as Transfecting Agents of DNA for Efficient Gene Delivery
por: Ju, Jia, et al.
Publicado: (2015) -
Binding of Gemini Bisbenzimidazole Drugs with Human Telomeric G-Quadruplex Dimers: Effect of the Spacer in the Design of Potent Telomerase Inhibitors
por: Paul, Ananya, et al.
Publicado: (2012) -
Further Studies on Cationic Gemini Amphiphiles as
Carriers for Gene Delivery—The Effect of Linkers in the Structure
and Other Factors Affecting the Transfection Efficacy of These Amphiphiles
por: Yadav, Mange Ram, et al.
Publicado: (2021) -
Characterization of cationic lipid DNA transfection complexes differing in susceptability to serum inhibition
por: Nchinda, Godwin, et al.
Publicado: (2002)