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Developmental Adaptation of Central Nervous System to Extremely High Acetylcholine Levels

Acetylcholinesterase (AChE) is a key enzyme in termination of fast cholinergic transmission. In brain, acetylcholine (ACh) is produced by cholinergic neurons and released in extracellular space where it is cleaved by AChE anchored by protein PRiMA. Recently, we showed that the lack of AChE in brain...

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Detalles Bibliográficos
Autores principales: Farar, Vladimir, Hrabovska, Anna, Krejci, Eric, Myslivecek, Jaromir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701655/
https://www.ncbi.nlm.nih.gov/pubmed/23861875
http://dx.doi.org/10.1371/journal.pone.0068265