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Developmental Adaptation of Central Nervous System to Extremely High Acetylcholine Levels
Acetylcholinesterase (AChE) is a key enzyme in termination of fast cholinergic transmission. In brain, acetylcholine (ACh) is produced by cholinergic neurons and released in extracellular space where it is cleaved by AChE anchored by protein PRiMA. Recently, we showed that the lack of AChE in brain...
Autores principales: | Farar, Vladimir, Hrabovska, Anna, Krejci, Eric, Myslivecek, Jaromir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701655/ https://www.ncbi.nlm.nih.gov/pubmed/23861875 http://dx.doi.org/10.1371/journal.pone.0068265 |
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