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Nourseothricin N-Acetyl Transferase: A Positive Selection Marker for Mammalian Cells

Development of Nourseothricin N-acetyl transferase (NAT) as a selection marker for mammalian cells is described. Mammalian cells are acutely susceptible to Nourseothricin, similar to the widely used drug Puromycin, and NAT allows for quick and robust selection of transfected/transduced cells in the...

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Detalles Bibliográficos
Autores principales: Kochupurakkal, Bose S., Iglehart, J. Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701686/
https://www.ncbi.nlm.nih.gov/pubmed/23861913
http://dx.doi.org/10.1371/journal.pone.0068509